With two antiviral drug candidates in the clinic, Durham, NC-based Chimerix has raised $45 million in a Series F round of financing. New Leaf Venture Partners led the round. The firm was joined by new investors Pappas Ventures and Morningside Group and existing contributors Canaan Partners, Sanderling Ventures, Alta Partners, Asset Management Company and Frazier [...]
Want proof that achieving FDA approval is more difficult than in the past? A study released by the BIO and BioMedTracker that the overall success rate for drugs moving through clinical trials to FDA approval from late 2003 to the end of 2010 is near one in 10. Previously the rate of approval were one [...]
A startling scientific breakthrough on Type 1 diabetes could help pave the way to a cure or perhaps significantly reduce the need for insulin therapy. A researcher at UT Southwestern, Dr. Roger Unger, reports in the February issue of Diabetes that by shutting down glucagon, a hormone that causes blood sugar to spike in patients [...]
A new target for the prevention of adverse immune responses identified as factors in the development of Alzheimer’s disease (AD) has been discovered by researchers at the University of South Florida’s Department of Psychiatry and the Center of Excellence for Aging and Brain Repair. The CD45 molecule is a receptor on the surface of the [...]
Calvert Labs is offering clients the same kind of 24/7 on-demand smartphone access to study information that’s available to the rest of the world for news and sports. It’s linked a project-tracking iPhone application with a near-real-time and on-demand filtered information source for preclinical researchers.
NPS Pharmaceuticals says that it’s on track to file for regulatory approval of Gattex after a late-stage study involving 86 patients demonstrated promising results for reducing the need for IV feeding among a majority of patients with short bowel syndrome. NPS now plans to file in the second half of the year and the news [...]
In a new study, scientists at the University of Maryland and the Institut Pasteur show that bacteria evolve new abilities, such as antibiotic resistance, predominantly by acquiring genes from other bacteria. The researchers new insights into the evolution of bacteria partly contradict the widely accepted theory that new biological functions in bacteria and other [...]
Scripps Research Institute scientists have converted adult skin cells directly into beating heart cells efficiently without having to first go through the laborious process of generating embryonic-like stem cells. The powerful general technology platform could lead to new treatments for a range of diseases and injuries involving cell loss or damage, such as heart disease, [...]
President Barack Obama said on Friday his healthcare overhaul is an important part of efforts to cut the budget deficit and insisted he will not “refight” the battle to pass the law. With emboldened Republicans vowing to repeal or replace the healthcare law he signed last March, Obama reiterated his case that the changes it [...]
Another week, another nano-prefixed word to add to the lexicon: NanoPopcorn. This one comes courtesy of researchers at Jackson State University in Mississippi who created a popcorn-shaped nanoparticle that can perform three separate tasks. First, it can detect as few as 50 prostate cancer cells, then it switches into thermal scalpel mode to cook the [...]
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