After many years of research, the reason behind what causes schizophrenia has finally come forward. Scientists, working in an international team, have finally discovered a gene mutation that is very strongly linked to causing schizophrenia. According to the researchers, the mutations in the VIPR2 gene increased the signaling in the vasoactive intestinal peptide pathway, which [...]
New research from the Virginia Bioinformatics Institute (VBI) has proven that there are very specific changes in the genetic makeup of people suffering from cancer and those who don’t have cancer. The researchers from VBI have developed a new technology that catches these genetic changes, which help in differentiating cancer patients from healthy individuals. The [...]
Scripps Research Institute scientists have converted adult skin cells directly into beating heart cells efficiently without having to first go through the laborious process of generating embryonic-like stem cells. The powerful general technology platform could lead to new treatments for a range of diseases and injuries involving cell loss or damage, such as heart disease, [...]
UCSF researchers have shown for the first time that the human fetal immune system arises from an entirely different source than the adult immune system, and is more likely to tolerate than fight foreign substances in its environment. The finding could lead to a better understanding of how newborns respond to both infections and vaccines, [...]
While it has become clear in recent years that susceptibility to pain has a strong inherited component, very little is known about actual “pain genes” and how they work. In the November 12th issue of Cell, researchers at Children’s Hospital Boston and their collaborators report on a novel human pain gene. People with minor variations [...]
New research provides the first direct evidence that attention-deficit/hyperactivity disorder (ADHD) is a genetic condition. Scientists at Cardiff University found that children with ADHD were more likely to have small segments of their DNA duplicated or missing than other children.
Genzyme Corp., a takeover target of Sanofi-Aventis SA, expects to complete sales of its diagnostics and pharmaceutical-ingredients units by the end of the year. Genzyme has six bidders for the drug business, Chief Financial Officer Michael Wyzga said today at an investor conference. Sale of the units will make Genzyme more appealing to potential buyers, [...]
The U.S. Court of Appeals in Washington has temporarily stayed a cut-off in government funding for human embryonic stem cell research. As a result of the stay, the Obama administration can fund embryonic stem cell studies as it appeals a decision banning government support for such research.
The results suggest that a buildup of that chemical, called glutamate, may play a role in the mechanism of migraines. An international scientific team has identified for the first time a genetic risk factor associated with common migraines and say their research could open the way for new treatments to prevent migraine attacks.
Milestone payments are becoming an increasingly familiar aspect of many biotech deals, as buyers try to mitigate the risks inherent with big purchases. Take Celgene’s $2.9 billion buyout of Abraxis; the biotech giant set aside $650 million in milestone payments if Abraxis’ key drug Abraxane hit certain goals. “These structures are a great way for [...]
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