Craig Venter has never been reluctant to credit himself for a lead role in sequencing the human genome. And he’s certainly not the least bit shy about placing a high value on the overall significance of the work. “I think it’s far more important than walking on the Moon; not much has happened since walking [...]
Researchers at Mount Sinai School of Medicine have for the first time differentiated human stem cells to become heart cells with cardiomyopathy, a condition in which the heart muscle cells are abnormal. The discovery will allow scientists to learn how those heart cells become diseased and from there, they can begin developing drug therapies to [...]
The scramble to come up with a faster and cheaper way to sequence a genome just got a credible new contender which aims to do the job for the bargain basement rate of $30. The first time scientists sequenced a human genome, the price tag hit $3 billion. That price point has quickly plunged to [...]
What three trends are most important to pharma these days? Generics, emerging markets and personalized medicine, according to the Harvard Business Review. Branded generics are the wave of Big Pharma’s future, HBR says. These branded versions of off-patent meds sell at higher prices than regular generics do, but are cheaper than the branded meds themselves. They give [...]
Tetraphase Pharmaceuticals has hauled in a $45 million C round–a hefty chunk of cash that will open a development runway stretching out up to two-and-a-half years. Over that time, CEO Guy Macdonald says the company will put its technology for developing a better breed of tetracycline antibiotics to the clinical development test, taking a lead [...]
For the first time, human embryonic stem cells have been cultured under chemically controlled conditions without the use of animal substances, which is essential for future clinical uses. The method has been developed by researchers at Karolinska Institutet and is presented in the journal Nature Biotechnology.
When muscle tissue experiences trauma or disease, such as muscular dystrophy, stem cells in the muscle known as “satellite cells” respond to repair and regenerate the muscle. These cells are particularly important in neuromuscular diseases, such as muscular dystrophy, which affect muscle stability and repair. Now, University of Missouri researchers have used time-lapse photography [...]
After birth the brain loses many nerve cells and this continues throughout life — most neurons are formed before birth, after which many excess neurons degenerate. However, there are some cells that are still capable of division in old age — in the brains of mice, at least. According to scientists from the Max Planck [...]
Three new genetic loci have been identified with involvement in subtle and quantitative variation of human eye color. The study, led by Manfred Kayser of the Erasmus University Medical Center Rotterdam, The Netherlands, is published May 6 in the open-access journal PLoS Genetics.
Scientists from Buffalo, Cleveland, and Oklahoma City made a huge step toward making the blind see, and they did it by using a form of gene therapy that does not involve the use of modified viruses. In a research report published in the April 2010 print issue of The FASEB Journal, scientists describe how they [...]
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