Milestone payments are becoming an increasingly familiar aspect of many biotech deals, as buyers try to mitigate the risks inherent with big purchases. Take Celgene’s $2.9 billion buyout of Abraxis; the biotech giant set aside $650 million in milestone payments if Abraxis’ key drug Abraxane hit certain goals. “These structures are a great way for [...]
A Utah doctor is being sent to jail for his connection to an illegal online pharmacy that sold more than eight million weight-loss pills manufactured in Mexico. Dr James A Brinton was sentenced to three years in a federal penitentiary after he pleaded guilty to conspiracy to distribute phentermine and conspiracy to commit international money [...]
Oncologics, lipid regulators, respiratory agents, antidiabetics and anti-ulcerants are the five largest drug classes by sales. But annual sales are only half the story. Which drug classes are booming, and which have plateaued–or even dropped? IMS Health has released top-line industry data revealing the 15 largest drug classes, and we’ve crunched the numbers to take a closer [...]
Eli Lilly (NYSE: LLY) is looking to its pipeline to fill the gaps left by a number of high-profile drugs coming off patent. In October 2011, blockbuster Zyprexa will fall to generic competition; additionally, about three-quarters of Lilly’s current revenue comes from eight drugs that will lose patent protection between now and 2017. ”We have the challenge [...]
A group of scientists have demonstrated that specially engineered stem cells could be used to fights off AIDS, successfully testing the approach in mice engineered to develop immune systems similar to humans. The investigators started with the observation that a small group of people who are virtually immune to HIV have disabled CCR5 receptors on [...]
For someone with a severe, incurable lung disorder such as cystic fibrosis or chronic obstructive pulmonary disease, a lung transplant may be the only chance for survival. Unfortunately, it’s often not a very good chance. Matching donor lungs are rare, and many would-be recipients die waiting for the transplants that could save their lives.
Building on research work undertaken in Germany, City of Hope investigators near LA have used modified stem cells loaded with gene sequences to fight off HIV. And the scientists in the study say that the work points to a possible cure for the dread virus, which has killed millions of people around the world.
A new, $50 million biomedical research lab has been completed at George Mason University near Washington D.C. and is being ramped up to study new therapies for infectious diseases–including a range of potential bioterror weapons. Once the 52,000-square-foot facility is licensed and fully operational in a few months, 50 people will be on site to [...]
While the overall economy may be flagging, Maryland says that its biotech industry is booming. And the governor wants to keep the momentum going with a few new industry incentives. Gov. Martin O’Malley told reporters that the biotech industry added more than a thousand jobs in the last three months; that’s 10 percent of the [...]
A group of molecular biologists and computer scientists at Stony Brook University have created a synthetic flu virus that can be used to develop a safer type of vaccine. The virus–A/PR/8/34–contains a scrambled genetic code generated by computer algorithms. The resulting mutations–what they describe as death by a thousand cuts–are arranged so the resulting [...]
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