Tag Archive for 'biomolecules'

Gene ‘Relocation’ Key to Most Evolutionary Change in Bacteria

In a new study, scientists at the University of Maryland and the Institut Pasteur show that bacteria evolve new abilities, such as antibiotic resistance, predominantly by acquiring genes from other bacteria. The researchers new insights into the evolution of bacteria partly contradict the widely accepted theory that new biological functions in bacteria and other [...]

Modulating Protein Could Help Control Alzheimer’s Disease

A protein known to exist in the brain for more than 30 years, called 5-lipoxygenase, has been found to play a regulatory role in the formation of the amyloid beta in the brain, the major component of plaques implicated in the development of Alzheimer’s disease, according to researchers at Temple University’s School of Medicine.

Fertilization Molecule Found

Researchers at the Swedish medical university Karolinska Institutet have been able to describe the 3D structure of a complete egg receptor that binds sperm at the beginning of fertilization. The results will lead to better understanding of infertility and may enable entirely new types of contraceptives.

Molecule Increases Survival of Stomach Cancer Patients

Stomach cancer patients with a high expression of the molecule microRNA 451 show greater survival rates. This molecule could be a biomarker for treatment response. “The high presence of microRNA 451 enhances the response to treatment with chemo-radiotherapy and increases the survival of patients with stomach cancer,” explained Dr. Jesús García-Foncillas, chief researcher of the [...]

Cockroach Brains May Be a Source of Antibiotics

Cockroach brains may be a source of new antibiotics capable of killing deadly drug-resistant bacteria, according to research that suggests the germ-spreading pests may be good for something after all. Insects such as cockroaches have a defense mechanism against bacteria, a “logical” development from living in unhygienic conditions, research from the U.K.’s University of Nottingham [...]

First Genetic Link to Common Migraine Found

The results suggest that a buildup of that chemical, called glutamate, may play a role in the mechanism of migraines. An international scientific team has identified for the first time a genetic risk factor associated with common migraines and say their research could open the way for new treatments to prevent migraine attacks.

‘Nanotox’ Research also has Implications for Nano Drug Delivery

A relatively recent subgroup of nanotech research is what is beginning to be commonly referred to as “nanotox,” or the study of how nanoparticles react to the environment and human body. It is a line of inquiry that directly arose out of concerns that if engineered nanoscale particles have the potential to do great things [...]

Drug Counterfeiting – a $200 Billion Business

Drug counterfeiting has become a $200-billion business annually, according to the World Customs Organization. By some calculations, the counterfeiting trade has become more lucrative than the narcotics business. It’s a global problem. The World Health Organization estimates that counterfeit drugs make up ten percent of the drug market worldwide. And experts say that solving it–or [...]

Drug Recalls Hit All-Time High

More drugs are hitting the recall list these days. As CNN Money reports, the number of recalls hit 1,742 last year–that’s an increase of 309 percent over 2008. “We’ve seen a trend where the last four years are among the top five for the most number of drug recalls since we began tallying recalls in [...]

Sanofi, Genzyme Far Apart on Buyout Price

The bidding on Genzyme has begun, with Sanofi putting down a hard offer of $69 a share, according to the Wall Street Journal. But Reuters and others have their own sources who say that Genzyme’s board wants to hold out for at least $80 a share, and possibly wait to see if another bidder steps [...]