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Drug Target Structure to Speed Up Drug Discovery

Scientists have found the solution to the three-dimensional structure of an important biological receptor. The impact of this finding has the potential to expedite drug discovery in many areas. Applications of this will range from arthritis to respiratory disorders to wound healing. This is because of the fact that it allows chemists to better research and design molecules for use in experimental drugs.

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Unpacking Condensins’ Function in Embryonic Stem Cells

Regulatory proteins common to all eukaryotic cells can have additional, unique functions in embryonic stem (ES) cells, according to a study in the Journal of Cell Biology. If cancer progenitor cells — which function similarly to stem cells — are shown to rely on these regulatory proteins in the same way, it may be possible to target them therapeutically without harming healthy neighboring cells.

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