Archive for the 'Immune Disorders' Category
July 27th, 2010 by admin
Oncologics, lipid regulators, respiratory agents, antidiabetics and anti-ulcerants are the five largest drug classes by sales. But annual sales are only half the story. Which drug classes are booming, and which have plateaued–or even dropped? IMS Health has released top-line industry data revealing the 15 largest drug classes, and we’ve crunched the numbers to take a closer look at the average sales growth of the 15 largest therapeutic classes over the last five years.
Continue reading ‘Fastest Growing Therapeutic Classes (by Sales)’
July 26th, 2010 by admin
Eli Lilly (NYSE: LLY) is looking to its pipeline to fill the gaps left by a number of high-profile drugs coming off patent. In October 2011, blockbuster Zyprexa will fall to generic competition; additionally, about three-quarters of Lilly’s current revenue comes from eight drugs that will lose patent protection between now and 2017. ”We have the challenge of replenishing our product portfolio from our pipeline,” says CEO John Lechleiter in a USA Today interview. “Fortunately, we have the most exciting pipeline today in our history.”
Continue reading ‘Pipeline to Soften Lilly Patent Losses’
July 23rd, 2010 by admin
A group of scientists have demonstrated that specially engineered stem cells could be used to fights off AIDS, successfully testing the approach in mice engineered to develop immune systems similar to humans. The investigators started with the observation that a small group of people who are virtually immune to HIV have disabled CCR5 receptors on their immune cells–a door the virus uses to infect the cells. The scientists engineered stem cells with the ‘door’ essentially locked, then inserted them into the mice, where they developed into immune cells that were able to guard the mice against HIV.
Continue reading ‘Specially Engineered Immune Cells Ward off AIDS’
July 9th, 2010 by admin
For someone with a severe, incurable lung disorder such as cystic fibrosis or chronic obstructive pulmonary disease, a lung transplant may be the only chance for survival. Unfortunately, it’s often not a very good chance. Matching donor lungs are rare, and many would-be recipients die waiting for the transplants that could save their lives.
Continue reading ‘Scientists Grow New Lungs Using ‘Skeletons’ of Old Ones’
July 8th, 2010 by admin
Building on research work undertaken in Germany, City of Hope investigators near LA have used modified stem cells loaded with gene sequences to fight off HIV. And the scientists in the study say that the work points to a possible cure for the dread virus, which has killed millions of people around the world.
Continue reading ‘Antiviral Stem Cell Squad Dispatched to Fight Deadly HIV’
May 26th, 2010 by admin
Researchers from the University of Colorado at Boulder believe a dry-powder, inhalable vaccine developed for measles prevention and slated for human clinical trials later this year in India may lead to similar–and cheaper–vaccines for illnesses ranging from tuberculosis to cervical cancer.
Continue reading ‘In-halable Measles Vax Holds Promise for Other Diseases’
April 15th, 2010 by admin
Infectious diseases are not always caused by infection. In work reported in the Journal of Experimental Medicine, researchers at Rockefeller University reveal that patients who suffer from a rare autoimmune disorder that makes them vulnerable to yeast infections produce antibodies that target and destroy immune-fighting proteins that would otherwise keep yeast in check.
Continue reading ‘Source of Recurrent Yeast Infections in Autoimmune Syndrome Pinpointed’
April 13th, 2010 by admin
Social influence plays a substantial role in the surging number of autism diagnoses, according to a study published in the American Journal of Sociology. The study, by researchers from the Institute for Social and Economic Research and Policy at Columbia University, found that children living near a child who has been previously diagnosed with autism have a much higher chance of being diagnosed themselves in the following year. The increased likelihood of being diagnosed is not due to environmental factors or contagious agents, the study found. Rather, it is due mainly to parents learning about autism from other parents who have a child diagnosed with the disorder.
Continue reading ‘Social Influence Plays Role in Surging Autism Diagnoses, Study Finds’
March 26th, 2010 by admin
Johns Hopkins scientists have found that a safe and inexpensive antibiotic in use since the 1970s for treating acne effectively targets infected immune cells in which HIV, the virus that causes AIDS, lies dormant and prevents them from reactivating and replicating.
Continue reading ‘Acne Drug Prevents HIV Breakout’
March 17th, 2010 by admin
Researchers at National Jewish Health and the University of Colorado School of Medicine have used a new strategy to develop cancer vaccines that are remarkably effective in mice. In the February 16 issue of the Proceedings of the National Academy of Sciences (PNAS), Kimberly Jordan, PhD, Jill Slansky, PhD, and John Kappler, PhD, report that 100 percent of the mice vaccinated with a peptide they developed remained alive and tumor-free for at least 60 days after inoculation with colon cancer cells. The research suggests a method for developing vaccines against a wide variety of cancers.
Continue reading ‘New Strategy Produces Promising Advance in Cancer Vaccines’
