Archive for the 'Vaccines' Category

Nasal Spray Vaccines More Effective against Flu

New research has shown that nasal vaccines are much more effective in providing protection against the flu. In fact the research also proved that nasal vaccines will soon protect not only against the flu and pneumonia, but also against bioterrorism agents such as Yersinia pestis that causes the plague. The research, presented at the Society for General Microbiology’s Spring Conference in Harrogate, presented Professor Dennis Metzger who described how including a natural immune chemical with standard vaccines has the potential to increase their protective impact when delivered through the nose.

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Novartis Completes $125M Acquisition of Tianyuan

Novartis has completed its acquisition of 85% in the Chinese vaccines firm Zhejiang Tianyuan Bio-Pharmaceutical. The deal, roughly valued at $125 million, was first announced in November 2009. Swiss drugs giant Novartis has said that the acquisition will provide it with an expanded presence in the Chinese vaccines market and also facilitate the introduction of additional Novartis’ vaccines into the country. The firms claims that China represents the world’s third largest vaccines market, with annual industry sales of over $1 billion, and the expectation of double-digit growth over coming years.

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Now – Nanoparticles for Long Lasting Immunity

Every vaccine scientist wants to discover just one thing – how to stimulate immunity that lasts for a lifetime! There are many live vaccines, such as the ones for smallpox and yellow fever that are able to stimulate immunity against the disease that lasts for many decades. However, in spite of the success of such vaccines, researchers are still unable to manufacture a vaccine that will provide lifetime immunity. Furthermore, vaccine scientists are also not able to understand how vaccines such as the smallpox one, induces such long lasting immunity.

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Inhalable Measles Vaccine Tested

Sustained high vaccination coverage is key to preventing deaths from measles. Despite the availability of a vaccine, measles remains an important killer of children worldwide, particularly in less-developed regions where vaccination coverage is limited. A team of researchers, led by scientists at the Johns Hopkins Bloomberg School of Public Health and the University of Colorado, developed and successfully tested a dry powder, live-attenuated measles vaccine that can be inhaled. The novel vaccine was studied in rhesus macaques.

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Researchers ‘Unzip’ MRSA’s Armor for Possible Vaccine

MRSA (methicillin-resistant staphylococcus aureus) is one tough nut to crack. Researchers have failed to produce a vaccine because agents cannot break through the life-threatening bacteria’s armor. So, while other research has targeted the surface of the bacteria, a team from the University of Rochester Medical Center has discovered an antibody that reaches beyond the microbe’s surface and can stop the MRSA bacteria from growing, according to a report in Drug Discovery & Development.

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GSK Malaria Vax Shows Promising Results

Mosquirix, an experimental malaria vaccine from GlaxoSmithKline, provides African children with long-lasting protection and reduces the risk of infection by the parasite that causes severe malaria by 46 percent over 15 months, according to researchers.

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H1N1 Vaccine Linked to 700% Increase in Miscarriages?

Recent data presented to the U.S. Centers for Disease Control and Prevention’s (CDC) Advisory Committee on Children’s Vaccines has revealed some shocking information about the effects of the H1N1 / swine flu vaccine on pregnant women. According to the National Coalition of Organized Women, the rate of miscarriage among pregnant women during the 2009 H1N1 / swine flu pandemic soared by over 700 percent compared to previous years, pointing directly to the vaccine as the culprit — but the CDC denies the truth and continues to insist nobody has been harmed.

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Experts Urge U.S. to Start Stockpiling Cholera Vaccine

As some project that Haiti will be hit with another 200,000 cholera infections in the next three months, experts from Harvard Medical School, George Washington University and the International Vaccine Institute are urging the U.S. to stockpile cholera vaccines. According to the experts, who wrote a perspective article in the New England Journal of Medicine, the costs are low, especially compared to the benefits for those inoculated.

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Higher Income Parents Forgoing Kids’ Vaccinations

Vaccination rates for children insured by commercial plans declined roughly four percentage points between 2008 and 2009. And experts fear that if this trend continues, the public’s health could be jeopardized.  ”Rates had been gradually improving in the commercial plans. This was the first time we’d seen a drop–and it was a pretty big drop,” said Sarah Thomas, vice president of public policy and communication for the National Committee for Quality Assurance, which recently released its annual State of Health Care Quality data.

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Charity Funds Brain Cancer Vaccine Trial

Cancer Research UK is set to begin a Phase I trial for glioblastoma, a deadly form of brain cancer. Forty-five patients have been recruited to receive the vaccine IMA950. The drug contains 11 peptides that are found in tumors but not healthy tissue. They “train” T cells in the immune system to recognize cancer cells as unhealthy cells–and then to target and destroy them. No other brain cancer vaccines in development work the same way. Cancer Research notes that using multiple peptides increases the chances of eliciting an immune response.

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