Archive for the 'New Drugs' Category
July 29th, 2010 by admin
Milestone payments are becoming an increasingly familiar aspect of many biotech deals, as buyers try to mitigate the risks inherent with big purchases. Take Celgene’s $2.9 billion buyout of Abraxis; the biotech giant set aside $650 million in milestone payments if Abraxis’ key drug Abraxane hit certain goals. “These structures are a great way for buyer and seller to share the risk that’s related to drug development,” says analyst Brett Skolnik. Milestones also encourage buyer and seller to look beyond the merger, making it more likely the deal will be beneficial to both sides in the long term.
Continue reading ‘Milestones Mitigate Risk in Biotech Deals’
July 27th, 2010 by admin
Oncologics, lipid regulators, respiratory agents, antidiabetics and anti-ulcerants are the five largest drug classes by sales. But annual sales are only half the story. Which drug classes are booming, and which have plateaued–or even dropped? IMS Health has released top-line industry data revealing the 15 largest drug classes, and we’ve crunched the numbers to take a closer look at the average sales growth of the 15 largest therapeutic classes over the last five years.
Continue reading ‘Fastest Growing Therapeutic Classes (by Sales)’
July 26th, 2010 by admin
Eli Lilly (NYSE: LLY) is looking to its pipeline to fill the gaps left by a number of high-profile drugs coming off patent. In October 2011, blockbuster Zyprexa will fall to generic competition; additionally, about three-quarters of Lilly’s current revenue comes from eight drugs that will lose patent protection between now and 2017. ”We have the challenge of replenishing our product portfolio from our pipeline,” says CEO John Lechleiter in a USA Today interview. “Fortunately, we have the most exciting pipeline today in our history.”
Continue reading ‘Pipeline to Soften Lilly Patent Losses’
July 20th, 2010 by admin
In the quest for a cancer vaccine, Merck KGaA is again stepping into the ring. Vaximm Holding AG, the company’s joint venture with a Switzerland’s BB Biotech Ventures III, will start testing a therapeutic cancer vaccine in patients next year. The vaccine, VXM01, harnesses the body’s immune system to fight cancer by using T-cells to close off the tumor’s blood supply. Roche’s Avastin also focuses on the tumor’s blood supply, but it focuses on eliminating a protein that creates the blood vessels to the tumor.
Continue reading ‘Merck KGaA’s Pancreatic Cancer Vaccine Ready for Testing’
July 15th, 2010 by admin
Hold onto your hats: The global market for contract manufacturing is headed for speedy growth over the next few years. According to a new report from RNCOS, pharmaceutical contract manufacturing is poised to grow about 12 percent per year from 2010 to 2012. Cost is one of the reasons, of course.
Continue reading ‘Contract Manufacturing to see Double-Digit Growth’
July 7th, 2010 by admin
The clock is ticking on Pfizer’s final, 18-month countdown on its $11.5 billion Lipitor franchise, but analysts are growing increasing fretful about the pharma giant’s ability to find new drugs to fill the looming revenue chasm. Pfizer had to admit that it suspended a slate of osteoarthritis trials after its highly touted pain drug tanezumab–billed as the world’s first likely biologic for pain–was linked to potentially perilous safety issues. And that came just two days after the company had to pull the cancer therapy Mylotarg from the market.
Continue reading ‘Pfizer’s Litany of Pipeline Snafus Cause Analysts to Fret’
July 5th, 2010 by admin
While the overall economy may be flagging, Maryland says that its biotech industry is booming. And the governor wants to keep the momentum going with a few new industry incentives. Gov. Martin O’Malley told reporters that the biotech industry added more than a thousand jobs in the last three months; that’s 10 percent of the state’s total tally of new jobs. And he touted a report from Battelle Technology Partnership Practice claiming that the state’s biotech industry has been expanding aggressively for the last several years.
Continue reading ‘MD Governor Touts a Booming Biotech Biz, New Jobs’
July 2nd, 2010 by admin
Craig Venter has never been reluctant to credit himself for a lead role in sequencing the human genome. And he’s certainly not the least bit shy about placing a high value on the overall significance of the work. “I think it’s far more important than walking on the Moon; not much has happened since walking on the Moon,” he tells the BBC on the tenth anniversary of the grand achievement, which took 2,000 scientists more than 10 years and $2.7 billion to accomplish.
Continue reading ‘Importance of Human Genome Sequencing Still Debated – 10 Years Later’
June 28th, 2010 by admin
Despite fears of cancer risks, despite abundant–and growing–competition, Lantus can power Sanofi-Aventis to its ambitious goals for growth in the diabetes arena. That’s what the company’s diabetes chief, Pierre Chancel, tells Bloomberg, anyway. Chancel says Lantus will continue to lead competitors, he says, even as longer-acting versions of insulin hit the market. “To beat Lantus, a product needs to show superiority in more than one parameter,” he told the news service. “We’re still not seeing that.”
Continue reading ‘“We’ll Make our Diabetes Goals,” Says Sanofi’
June 15th, 2010 by admin
What three trends are most important to pharma these days? Generics, emerging markets and personalized medicine, according to the Harvard Business Review. Branded generics are the wave of Big Pharma’s future, HBR says. These branded versions of off-patent meds sell at higher prices than regular generics do, but are cheaper than the branded meds themselves. They give a measure of assurance to patients worried about counterfeit meds–and to those concerned that unbranded generics won’t work as well as their branded counterparts. They also offer drugmakers a niche in emerging countries.
Continue reading ‘Pharma Trifecta: Generics, New Markets and Personalization’